Description
Description: JAM2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 452 amino acids (29-238a.a.) and having a molecular mass of 50.7kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). JAM2 is expressed with a 239 amino acid hIgG-His-tag at C-Terminus and purified by proprietary chromatographic techniques.
Introduction: Junctional Adhesion Molecule 2 (JAM2) is a member of the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein which is localized at the tight junctions of both epithelial and endothelial cells. JAM2 functions as an adhesive ligand for interacting with various immune cell types, and may have a role in lymphocyte homing to secondary lymphoid organs